Researchers from Ecole Polytechnique Fédérale of Lausanne (EPFL), Ca 'Foscari of Venice, and the University of Padua have established a method to sustainably produce and quickly identify thousands of macrocyclic compounds, a family of pharmaceutical molecules of great interest for the treatment of serious diseases such as tumors.
Published in Nature Communications, the study entitled Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale show how acoustic wave technology allowed the parallel synthesis of multiple different chemical compounds in tiny reaction drops.
Reference Link:https://www.unipd.it/
